Master of Health Informatics

Drive data-informed solutions and advance health equity with an online Master of Health Informatics. Through partnerships with the Carolinas Simulation Center, Wake Forest School of Medicine, and Advocate Health, this program offers real-world experience in patient-centered research and innovation.

At a Glance

8 days left to apply
Average 2 Years to Completion
Start date: May 11, 2026
Expert Faculty Mentorship

Why Choose Wake Forest’s Online MHI?

Go beyond theory with a combination of technical training and leadership development to prepare you to make an impact across the healthcare systems you serve. You’ll gain the skills to turn data into meaningful, equitable outcomes.

As an Academic Educational Partner of the Healthcare Information and Management Systems Society (HIMSS), Wake Forest SPS meets rigorous educational standards and provides students with access to certification resources, professional development, and a powerful network of industry leaders. Plus, all students receive a free individual HIMSS membership and the opportunity to attend the annual HIMSS Global Health Conference & Exhibition.

Master of Health Informatics Core Courses

You’ll complete 10 required online courses, including a capstone that brings everything together. Each course lasts 7.5 weeks. There’s no required order for these courses, so you are free to take courses in the sequence that works best for your schedule, depending on availability.

Health Informatics Today
This course serves as an introduction to health informatics concepts, techniques, and emerging trends, with a leadership lens. Learners will identify current and emerging trends in health informatics, including electronic health records, patient portals, health data, standards, sourcing, accessibility, health equity awareness, and privacy issues. The course will cover how health informatics is used in administrative, operational, clinical, financial, and strategic aspects of healthcare, and how healthcare technologies are used in information management to deliver and improve the quality, cost, equity, and accessibility of healthcare services.
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Population Health & the American Healthcare System
This course provides a thorough overview of healthcare delivery in the United States and Population Health. Learners will discuss the importance of healthcare and health information quality and the need for health equity and patient safety in healthcare systems, and analyze the impact of social, behavioral, cultural, economic, and environmental factors on healthcare systems and practices. The course will cover ways to create sustainable change through improved management, policy, and financial support in healthcare, including relevant governmental, ethical, regulatory, and compliance issues in the context of healthcare plans and payment models.
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Healthcare Data Analytics
A comprehensive introduction to the current state of the science and practice of analytics in healthcare, including how to “tell the story” the numbers present. Core competency skills are achieved using a variety of learning methods to help students apply analytic techniques supporting data mining, visualization and data driven decision making.
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Healthcare Databases
Dive into the theory and application of database management systems. This course will help learners apply principles of database management, data modeling, privacy, and cybersecurity to improve healthcare and manage health data effectively, and identify and analyze database management systems. It will also cover query languages and the design and maintenance of cloud databases.
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Digital Health
This course will explore the theory, applied practice, and impact of current and emerging digital health technologies and clinical documentation systems for all demographics. Learners will differentiate between the technology tools used in healthcare, including wearables, telemedicine, Mobile Health, Internet of Things (IoT), and other Consumer eHealth tools, and examine how digital health solutions and patient portals impact patients’ health and wellness, access to healthcare services, and interactions with their caregivers (patient perspective). They will also evaluate how digital platforms can improve and transform clinical operations and the delivery of healthcare (care provider perspective).
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Health Information Regulation, Privacy & Security
This course offers foundational exposure to legal and ethical issues related to health information privacy and security, and the basic technological considerations to meet professional obligations in health informatics practice. Learners will evaluate security audits, regulatory policies/laws, and release of information procedures, and address ethical considerations in health sciences, informatics, and electronic medicine. They will discuss legal and regulatory issues that apply to the management of patient information in health informatics and how they can be a source of innovation. The course will also cover evolving standards and issues, such as blockchain, remote patient monitoring, telemedicine, and their regulatory, privacy, security, and ethical issues.
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Healthcare Leadership and Impact
This course will explore leadership, organizational structure, and effective team functioning in healthcare. It will provide students with an understanding of the importance of developing high-quality relationships, the impact of motivation, power, and influence, principles of organizational ethics, and health equity.
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Quality and Patient Safety Management in Healthcare
This course covers the foundations for understanding and pursuing patient safety and quality of care outcomes within the current healthcare environment. Thoughtful consideration is given on how quality and safety from a global perspective can critically impact expectations within today’s healthcare environment.
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Capstone in Health Informatics
This course threads together all program content learned throughout the program into a culminating capstone experience. Learners will identify a current health care opportunity, challenge, or issue, and develop and implement a comprehensive Health Informatics project, case study, or business case. Students will design a process or project that positively impacts and improves outcomes using the principles and applied concepts of health informatics.
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Master of Health Informatics Electives

You will choose 1 elective to take at any time during the program when your selection is available. Wake Forest SPS designs electives with flexibility and relevance in mind. You’ll have access to a wide range of courses across all programs, so you can tailor your learning and deepen your expertise to meet your goals.

Project Management Essentials
Gain a deeper understanding of the foundational concepts of project management, including an overview of the project lifecycle as defined in the Project Management Body of Knowledge. This course also dives into areas such as risk, scope, schedule, quality, monitoring, and communication.
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Telehealth Today and Tomorrow
This course will provide an overview of the tools, techniques, opportunities, and challenges associated with telehealth from an informatics perspective. Learners will describe technologies used to deploy and improve telehealth for better healthcare access, identify strategies to engage patients in using telehealth practices, understand the impact of telehealth on different patient populations, and describe the clinical, legal, regulatory, and quality issues in the use of telehealth.
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Artificial Intelligence for Health Informatics
This course will review the foundations of artificial intelligence (AI) with applications to the prevention, detection, diagnosis, and prognosis of diseases. Learners will differentiate various artificial intelligence concepts and enabling technologies, and discover and employ processes used in designing and implementing artificial intelligence systems to prevent bias and inequities.
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The people who develop & continually refine programs bring expertise from…

Ready to
start your tomorrow?

Your goals are within reach—and we’re here to help you get there.

Meet the Master of Health Administration Academic Director

Meet the Experts Guiding Your Journey

Debra Wolf, Academic Director of the Master of Health Informatics program
Debra Wolf, Ph.D., MSN, BSN, RN, FAAOHN
Academic Director and Professor of the Practice in Health Informatics & Health Administration
Wake Forest University
Hasan Sapci
Hasan Sapci, M.D.
Health Informatics Faculty
Wake Forest University
Sue Evans
Susan Evans, MSN, BSN, RN-BC
Health Informatics Faculty
Wake Forest University
Cariann Johnson-Huber
Cariann Johnson-Huber DNP, MSN, RN
Health Informatics Faculty
Wake Forest University
Mountasser Kadrie
Mountasser Kadrie, Ph.D.
Health Informatics Faculty
Wake Forest University
Ruth Kyrstopolski
Ruth A. Krystopolski, MBA
President, Ayin Health Solutions and Health Informatics Faculty
Wake Forest University
Headshot of Saira Haque, a Program Advisory Board member for the Wake Forest SPS Master of Health Informatics program
Saira Haque, PhD, MHSA, FAMIA, ACHIP
Senior Director, Clinical Informatics
Pfizer Medical Affairs
A headshot of Lisa Lucas in a blue shirt
Lisa Lucas, DNP, MBA, MHCM, RN-BC Informatics
National Director of Healthcare Informatics
SAS
Jennifer Houlihan
Enterprise VP, Population Health
Advocate Health
Dawn Ross
Dawn M. Ross, DNP, RN-BC
Vice President & Chief Clinical Informatics Officer
Atrium Health
Eric Kirkendall, MD, MBI
CMIO/CIO - Academic IT
Wake Forest School of Medicine
Chris Sakalosky
Chris Sakalosky
Vice President, Strategic Industries, Google Cloud
Google Cloud

Where Your MHI Can Take You

Earning a Master of Health Informatics degree equips you for high-demand roles in clinical informatics, health IT, data analytics, and digital health innovation. There is an increasing need for skilled professionals who can turn data into better outcomes with employment in medical information fields projected to grow 17% by 2031 (Bureau of Labor Statistics).

Whether advancing in your current role or pivoting to a new path, your MHI opens doors to high-impact careers at the intersection of health and technology.

The Students of Wake Forest SPS